In asystem for tailoring an injection protocol to an individual patient, the injection protocol to be administered in connection with a diagnostic imaging procedure, the system comprises (a) a processor for controlling operation of the system； and (b) a programming system operably associated with the processor. The programming system has at least one algorithm for enabling: (i) identification of a patient transfer function for an individual patient based on data specific to the individual patient wherein the patient transfer function enables prediction, in response to a given input, of a desired level of enhancement to be output from each of one or more regions of interest of the individual patient； (ii) updating of the patient transfer function using a portion of scan data acquired as a result of a test scan of the one or more regions of interest of the individual patient while a fluid inclusive of a contrast enhancing fluid therein propagated therethrough； and (iii) determination through a numerical optimization technique of the given input that, when entered into the patient transfer function, determines an injection protocol for the individual patient with which to generate the desired level of enhancement to be output from each of the one or more regions of interest.
