KLEIN THOMAS,KLEY HANS-PETER,HATZELMANN ARMIN,ELTZE MANFRID
申请号：
PL36947202
公开号：
PL210463B1
申请日:
2002.09.17
申请国别(地区):
PL
年份:
2012
代理人:
摘要：
The invention relates to the combined use of a PDE4 inhibitor and a conventional NSAID in the treatment of an inflammatory disease and/or an inflammation-associated disorder while minimizing gastrointestinal side effects, such as gastric erosions and ulcer, which are frequently associated with the use of conventional NSAIDs. A preferred PDE 4 inhibitor for this combination is roflumilast or a derivative thereof. A preferred conventional NSAID for this combination is diclofenac or a derivative thereof.
