THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;ADVAXIS, INC.
发明人:
YVONNE PATERSON,JOHN ROTHMAN,VAFA SHAHABI
申请号：
PT08754370
公开号：
PT2155243E
申请日:
2008.05.12
申请国别(地区):
PT
年份:
2015
代理人:
摘要：
A recombinant Listeria strain expressing a kallikrein-related peptidase 3 (KLK3) peptide, wherein the sequence of the KLK3 peptide comprises a sequence selected from SEQ ID NOs: 27, 29-32, 34, and 36-39, or a sequence greater than 95% identical thereto, wherein the KLK3 peptide is in the form of a fusion peptide and further comprises a non-KLK3 peptide, wherein the non-KLK3 peptide is an ActA peptide or a PEST sequence, and wherein the non-KLK3 enhances the immunogenicity of the fusion peptide.
