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Antibodies specific for tgf-beta
专利权人:
XOMA TECHNOLOGY LTD.
发明人:
BEDINGER DANIEL,KHAN SHIREEN S.,MIRZA AMER,NARASIMHA AJAY J.,TAKEUCHI TOSHIHIKO
申请号:
NZ61875712
公开号:
NZ618757A
申请日:
2012.06.01
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
Disclosed is an antibody that binds transforming growth factor beta (TGF&bgr;)1, TGF&bgr;2 and TGF&bgr;3 comprising: (a) a heavy chain CDR1 amino acid sequence GGTFSSYA, or a variant thereof in which one or two amino acids have been changed; (b) a heavy chain CDR2 amino acid sequence IIPIFGTA, or a variant thereof in which one or two amino acids have been changed; (c) a heavy chain CDR3 amino acid sequence ARGLWEVRALPSVY, or a variant thereof in which one or two amino acids have been changed; (d) a light chain CDR1 amino acid sequence DIGSKS, or a variant thereof in which one or two amino acids have been changed; (e) a light chain CDR2 amino acid sequence set forth in EDI, or a variant thereof in which one or two amino acids have been changed; and (f) a light chain CDR3 amino acid sequence QVWDRDSDQY, or a variant thereof in which one or two amino acids have been changed.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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