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ANTI-TUMOR PLANT-MEDICAMENT SUSTAINED-RELEASE TABLET OF ELEMENE
专利权人:
Tian Xie
发明人:
Tian Xie,Haizhu Fan,Xiaori Zhan,Chenglu Li,Zhaowu Zeng
申请号:
US13697138
公开号:
US20130059922A1
申请日:
2011.04.08
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed is an anti-tumor plant-medicament sustained-release tablet of elemene which comprises an elemene as an active component and is prepared by formulation of the elemene, a sustained-release agent, a bulking agent, a disintegrating agent, a binder and a lubricant, each component above-mentioned being in the following weight composition: the elemene 10%-15%, the sustained-release agent 3%-15%, the bulking agent 45%-70%, the disintegrating agent 3%-8%, the binder 1%-10%, and the lubricant 1%-8%. The sustained-release tablet of elemene provided in the invention has properties of expansion and adhesion, which in turn enables extending the retention time of the drug on upper and middle sections of the gastrointestinal tract. Therefore, the tablet may be taken b.i.d.×3, in order to attain reduction in fluctuation of the plasma concentration, maintain effective plasma concentration for a longer period, and reduce the irritation on the gastrointestinal tract. The skeleton-type sustained- and controlled-release formulation has advantages of low cost, easy control, and easy industrialized production.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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