Disclosed is a modular aeroponic system that accommodates different support-mediums and misting or spray configurations. In one embodiment, the disclosed system comprises: a root chamber with plumbing that is coupled to a nutrient distribution system； a first interchangeable-lid for the root chamber that functions as a first type of support medium； a second interchangeable-lid defined a surface by a plurality of net pot receptacles for retaining a plurality of net pot support mediums； a first spray-nozzle manifold that may be removably coupled to the plumbing of the root chamber and featuring spray nozzles in a first configuration； a second spray-nozzle manifold that may be removably coupled to plumbing of the root chamber and featuring spray nozzles in a second configuration； wherein the first and second lid may be interchangeably applied to the root chamber； and wherein the first and second manifold may be interchangeably coupled to the root chamber's plumbing.
