A nasal powder dispenser device having a reservoir containing at least one dose of powder； a nasal dispenser head for inserting into a user's nostril, the nasal dispenser head including a dispenser orifice； and an air expeller that, during actuation of the nasal powder dispenser device, generates a flow of compressed air so as to dispense a dose of powder into the nostril through the dispenser orifice. The air expeller has an air chamber and a piston that slides in airtight manner in the air chamber so as to compress the air contained in the air chamber. In the nasal powder dispenser device, a pressure of the flow of compressed air generated by the air expeller is higher than 0.7 bar； and a volume of the air chamber is greater than 1700 mm3.
