Wen Zhang,Jennifer Riggs-Sauthier,J. Milton Harris,Michael D. Bentley
申请号：
US15788626
公开号：
US20180256599A1
申请日:
2017.10.19
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention provides corticosteroids that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits a reduced biological membrane crossing rate as compared to the biological membrane crossing rate of the corticosteroid not attached to the water-soluble oligomer.
