ШЕНЬ Ван (US),ЧЖАН Аймин (US),ФАНЬ Цзюньфа (US),ЧЖЭН Сяолин (US)
申请号:
RU2012103492/04
公开号:
RU2012103492A
申请日:
2010.07.02
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. A compound of Formula A: wherein W is N or a C-CN group R is a substituted monocyclic, bicyclic or tricyclic aryl group, or a heteroaryl group or an arylalkyl group R is hydrogen, halogen, cyano, nitro, trifluoromethyl, difluoromethyl, trifluoromethoxy, difluoromethoxy, C-C 1 -C 6 alkyl, C 1 -C 6 alkenyl, C 1 -C 6 alkynyl, C 1 -C 6 cycloalkyl, C 1 -C 6 cycloalkylalkyl, heterocyclyl, heterocyclylalkyl, -NRSOR, -SONRR, -C (O) R, -C (O) OR, -OC (O) R , -NRC (O) OR, -NRC (O) R, -C (O) NRR, -NRR, -NRC (O) NRR, -OR, -S (O) R, -SOR or -SR, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, heterocyclyl and heterocyclylalkyl wish to set up unsubstituted or optionally substituted with up to five groups independently selected from the group consisting of oxo, halogen, C-Ci ^ alkyl, C-alkenyl, C-Calkinila, C-Ctsikloalkila, C-Ctsikloalkilalkila, cyano, trifluoromethyl, difluoromethoxy, trifluoromethoxy, azido, -NRSOR, -SONRR, -C (O) R, -C (O) OR, -OC (O) R, -NRC (O) OR, -NRC (O) R, -C (O) NRR, -NRR, -NRC (O) NRR, -OR, -S (O) R, -SOR, -SR, heterocyclyl and heterocyclylalkyl T represents a bond or a divalent radical formed by removal of an additional hydrogen atom from C 1 -C 6 alkyl, C C1-6 alkenyl, C1-C4 alkynyl, C1-C6 cycloalkyl, C1-C6 cycloalkylalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, heterocyclyl or heterocyclylalkyl wherein each said alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heteroaryl and heterocyclyl is unsubstituted or optionally substituted by no more than three groups independently selected from the group consisting of oxo, halogen, C1-C4 alkyl, C1-C6 alkenyl, C2-C6 alkynyl, cyano, trifluoromethyl, difluoromethoxy, trifluoromethoxy, azido, -NRSOR, -SONRR, -C (O) R, -C (O) OR, -OC (O) R, -NRC (O) OR, -NRC (O) R , -C (O) NRR, -NRR, -NRC (O) NRR,