The present invention provides a novel device, method and kit for reconstitution of a solid or semi-solid pharmaceutical composition by a negative pressure differential comprises (i)a first adapter (101) comprising a first connector (114), a first peripheral wall (103) wherein the first adapter (101) is coupled to the first vial (10) by means of a first connector (114) (ii)a second adapter (102) comprising a second connector (118), a second peripheral wall (104) wherein the second adapter (102) is coupled to the second vial (20) by means of a second connector (118) (iii)a transfer port (105) wherein the transfer port comprises a first end (112) ending in first adapter (101) to gain access to first vial (10) and a second end (116) ending in second adapter (102) to gain access to second vial (20) wherein the first adapters (101) and the second adapter (102) are joined together in vertical direction by means of horizontal wall (150) Wherein the adapter (101, 102) connected to the vials (10, 20) by means of the ends (112, 116).
