An electrocardiogram (ECG) signal processing system is provided. The ECG signal processing system comprises an analog-to-digital converter (ADC) configured to convert an input analog ECG signal into a digital ECG signal, and a digital signal processing engine (DSPE) coupled to the ADC to receive the digital ECG signal. The DSPE is configured to decompose and reconstruct the digital ECG signal. A dynamic system clock source is coupled to the ADC and the DSPE for dynamic signal sampling, the dynamic system clock source clocking the ADC and the DSPE at a first frequency f1 to detect one or more first parameters of the input analog ECG signal and at a second frequency f2 to detect one or more second parameters of the input analog ECG signal.
