A sound signal generation device includes a sound information acquirer acquiring biological information of a subject user, a change timing determiner determining a change timing that allows a first piece of sound information to be changed to a second piece of sound information in a cycle corresponding to the biological information acquired by the biological information acquirer, a sound signal generator generating a sound signal based on the second piece of sound information at a timing determined by the change timing determiner, and an amplitude of a waveform of a sound signal generated by the sound signal generator based on at least one piece of sound information, among a plurality of pieces of sound information including the first piece of sound information and the second piece of sound information, generally decreases from a maximum amplitude point, in which the amplitude is maximized, towards the end of the waveform, or generally increases from the start of the waveform towards a maximum amplitude point, in which the amplitude is maximized.
