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МИКРОКАПСУЛЬНЫЙ ПРЕПАРАТ НА ОСНОВЕ АЛЬГИНАТА-АЦИЛЬНЫХ ПРОИЗВОДНЫХ ХИТОЗАНА, ЕГО ПОЛУЧЕНИЕ И ПРИМЕНЕНИЕ
专利权人:
ДАЛЯНЬ ИНСТИТЬЮТ ОФ КЕМИКАЛ ФИЗИКС; ЧАЙНИЗ АКАДЕМИ ОФ САЙЕНСЕЗ (CN)
发明人:
МА Сяоцзюнь (CN),ЮЙ Вэйтин (CN),СЕ Хунго (CN),ЛЮ Сюдун (CN),СЕ Вэйян (CN),ЧЖЭН Гошуан (CN)
申请号:
RU2013129219/15
公开号:
RU2013129219A
申请日:
2011.11.28
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. The microcapsule formulation based on alginate-acyl derivatives of chitosan prepared by mixing microcapsules of alginate-acyl derivatives of chitosan with an aqueous solution, where the microcapsule structure consists of two parts: the microcapsule membrane and the inner core wherein the membrane is a microcapsule polielektrolitnokompozitnuyu hydrogel membrane formed chitosan, alginates and acyl derivatives of chitosan, and the inner core is a hydrogel or alginate liquid medium containing kletki.2. Microcapsule formulation according to claim 1, characterized in that in the preparation of microcapsules are spherical microcapsules having a particle size of 10 to 2000 microns. membrane thickness is from 0.1 to 100 microns, and the molecular weight of alginate, forming the membrane is from 10 kDa to 2,000 kDa chitosan material has a degree of deacetylation of from 70 to 98% and a molecular weight of from 1 kDa to 500 kDa the molecular weight of the acyl derivatives of chitosan is from 1 kDa to 800 kDa the weight ratio of chitosan, alginate, and acyl derivatives of chitosan is from 1: 0: 0.1 to 10: 1: 10 and alginate concentration in the core ranges from 0.1 to 50 g / l.3. Microcapsule formulation according to claim 1 or 2, characterized in that in the preparation acyl derivatives of chitosan in the microcapsule are N-acyl chitosan monomer with the structure shown below: wherein R represents formyl, acetyl, propionyl, butyryl, valeryl or caproyl. degree of substitution of the acyl derivative is from 10 to 60% molecular weight chitosan shell material is from 1 to 400 kDa and the degree of deacetylation is composed1. Микрокапсульный препарат на основе альгината-ацильных производных хитозана полученный посредством смешения микрокапсул из альгината-ацильных производных хитозана с водным раствором, где структура микрокапсулы состоит из двух частей: мембраны микрокапсулы и внутреннего ядра при этом мембрана микрокапсулы представляет собой полиэлектролитнокомпозитную гидроге
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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