WOOLFORD, ALISON JO-ANNE,HOWARD, STEVEN,BUCK, ILDIKO MARIA,CHESSARI, GIANNI,JOHNSON, CHRISTOPHER NORBERT,TAMANINI, EMILIANO,DAY, JAMES EDWARD HARVEY,CHIARPARIN, ELISABETTA,HEIGHTMAN, THOMAS DANIEL,FRE
申请号:
CA2831346
公开号:
CA2831346A1
申请日:
2012.04.20
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention relates to bicyclic heterocycle compounds of formula (I): or tautomeric or stereochemically isomeric forms, N-oxides, pharmaceutically acceptable salts or the solvates thereof; wherein R1, R2a, R2b, R3a, R3b, R5, R6, R7, R8, R9, p and E are as defined herein; to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.