Provided herein are synergistic herbicidal compositions containing (a) a com pound of formula (I): 4-amino-3-chloro-5- fluoro-6-(4-chloro-2-fluoro-3- methoxyphenyl)pyridine-2-carboxylic acid or a derivative thereof, or an agriculturally accept able salt or ester thereof and (b) a protoporphyrinogen oxidase inhibitor, e.g., acifluorfen, azafeniden, bifenox, carfentrazone-ethyl-ethyl, flumioxazin, ipfencarbazone, oxadiargyl, oxadiazon, oxyfluorfen, pentoxazone, pyraclonil, pyraflufenethyl and saflufenacil, or a salt or ester thereof. The compositions and methods provided herein provide control of undesirable vegetation, e.g., in direct- seeded, water-seeded and transplanted rice, cereals, wheat, barley, oats, rye, sorghum, corn or maize, sugarcane, sunflower, oilseed rape, canola, sugar beet, soy bean, cotton, pineapple, pastures, grasslands, rangelands, fallowland, turf, tree and vine orchards, aquatics, plantation crops, vegetables, industrial vegetation management (IVM) and rights-of-way (ROW).