A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent

• 收藏
• 分享

专利权人:

MannKind Corporation

发明人:

Grant, Marshall,Wilson, Bryan R.

申请号：

AU2013205432

公开号：

AU2013205432A1

申请日:

2013.04.26

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

#$%^&*AU2013205432A120130523.pdf#####A METHOD FOR IMPROVING THE PHARMACEUTICAL PROPERTIES OF MICROPARTICLES COMPRISING DIKETOPIPERAZINE AND AN ACTIVE AGENT Abstract r 45 301,/3 0.4 (13 0.6 0.7 0A8 0.9 1.1)L Atomization Ilr* sstire (bair) Methods are provided for drying a particle. Specifically, there is provided a spray-dried diketopiperazine-insulin particle formulation having improved aerodynamic performance and in which the active agent is more stable and efficiently delivered as compared to that of the lyophilized diketopiperazine-insulin formulation. The dry powders have utility as pharmaceutical formulations for pulmonary delivery,

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/