A volumetric integral phase-shift spectroscopy (VIPS) device for detecting evidence of a stroke in a patient may include a frame including a housing, at least one VIPS receiver in the housing, circuitry in the housing coupled with the at least one VIPS receiver, two wrap-around ends, configured to wrap around the back of the patient's head and over the ears, a first VIPS transmitter in one of the two wrap-around ends, a second VIPS transmitter in the other of the two wrap-around ends, and a processor. The first and second VIPS transmitters and the at least one VIPS receiver may measure multiple phase shifts and/or multiple amplitudes in a fluid and/or a tissue in the patient's head. The processor may determine that the multiple phase shifts and/or multiple amplitudes matches a predefined stroke-specific VIPS signature and thus detect evidence of a stroke.