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VACCINS DE VIRUS RESPIRATOIRE SYNCYTIAL (RSV) D'ANKARA DE VIRUS À VACCIN MODIFIÉ RECOMBINANT (MVA)
专利权人:
Bavarian Nordic A/S
发明人:
申请号:
EP19211547.5
公开号:
EP3656396A1
申请日:
2013.03.15
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Provided herein are recombinant modified vaccinia virus Ankara (MVA) strains as improved vaccines against infection with Respiratory Syncytial Virus (RSV virus) and to related products, methods and uses. Specifically, provided herein are genetically engineered recombinant MVA vectors comprising at least one nucleotide sequence encoding an antigenic determinant of an RSV membrane glycoprotein and at least one nucleotide sequence encoding an antigenic determinant of an RSV nucleocapsid protein. Also provided herein are products, methods and uses thereof, e.g., suitable to affect an immune response in a subject, or suitable to diagnose an RSV infection, as well as to determine whether a subject is at risk of recurrent RSV infection.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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