A method for providing guidance in Cardiac Resynchronization Therapy (CRT) comprising: a) providing image data sets of the heart of a patient; b) creating a three-dimensional (3D) anatomical model of the cardiac structures; c) calculating myocardium infarct scar distribution; d) calculating heart mechanical activation data; e) superimposing the scar distribution and the mechanical activation data on the 3D anatomical model to obtain a 3D roadmap model including anatomical geometry and mechanical activation data. A corresponding device and computer program are also model disclosed.