Akila Jayaraman,Karthik Viswanathan,Rahul Raman,Zachary H. Shriver,Ram Sasisekharan
申请号：
US12829931
公开号：
US09278998B2
申请日:
2010.07.02
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention provides HA polypeptides (e.g., H1 HA polypeptides) that bind to umbrella-topology glycans, and reagents and methods relating thereto. The present invention provides binding agents that bind to HA polypeptides (e.g., H1 HA polypeptides), and reagents and methods relating thereto. The present invention provides interfering agents that inhibit the binding of HA polypeptides (e.g., H1 HA polypeptides) to HA receptors, and reagents and methods relating thereto. The present invention provides compositions and methods for treating, preventing, and/or diagnosing influenza infection utilizing HA polypeptides, HA polypeptide binding agents, HA polypeptide interfering agents, and/or vaccine compositions comprising any of the foregoing.
