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PREDICTING RESPONSE TO A HER DIMERISATION INHIBITOR BASED ON LOW HER3 EXPRESSION
专利权人:
F. HOFFMANN-LA ROCHE AG;GENENTECH, INC.; INC.;GENENTECH
发明人:
AMLER, LUKAS, C,BIRKNER, MERRILL,LIN, CHIN-YU,MOECKS, JOACHIM,STRAUSS, ANDREAS
申请号:
NZ57882408
公开号:
NZ578824A
申请日:
2008.02.29
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is the use of a HER2 dimerization inhibitor antibody that binds to a heterodimeric binding site of HER2 in the manufacture of a medicament for treating a patient with ovarian, peritoneal, or fallopian tube cancer, wherein the patient's cancer has been determined to express HER3 at a level less than the median level for HER3 expression in the cancer type. Said HER2 dimerization inhibitor antibody can be pertuzumab.
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中国工程科技知识中心
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