ANNEAU VAGINAL COMPRENANT DE LA DHEA OU DU SULFATE DE DHEA ET EVENTUELLEMENT UN AGENT MODULATEUR DE LA LIBERATION DU PRINCIPE ACTIF, UTILE POUR AUGMENTER LA RESERVE OVARIENNE CHEZLES FEMMES ET POUR ATTENUER LES SYMPTOMES ASSOCIES A LA MENOPAUSE
FUENTES GARCIA, FRANS ARIEL,CHEN, SHU-CHEN,BELTRAN APABLAZA, MARIANELA DEL CARMEN
申请号：
CA2860133
公开号：
CA2860133C
申请日:
2011.12.29
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Sustained-release vaginal ring for comprising dehydroepiandrosterone(DHEA), dehydroepiandrosterone sulfate (DHEA-S) or pharmaceuticallyacceptable thereof as active principle, and optionally a release-modulatingagent of the active principle, wherein the amount of active principle isbetween1% to 32% by weight, relative to the total weight of the formulation, and themodulator is selected from: polyvinylpyrrolidone K-30, lactose,microcrystallinecellulose and sodium lauryl sulfate. The vaginal ring of the present inventioncan be used to increase ovarian reserve in women, to be used as drug inassisted reproduction programs, and to relieve symptoms associated withmenopause, such as symptoms of vulvar and vaginal atrophy and sexualdysfunction in postmenopausal women.
