Sterilization and cleaning of an escalator hand rail are performed. A sterilization and cleaning device including a hand rail a plasma source for irradiating the hand rails with ions or radicals or UV light an enclosure for housing the plasma source a power source for generating plasma a fan for generating relatively negative pressure in the enclosure filter units for removing removed bacteria, viruses, and organic matters such as hand marks and filter plates located backward and forward of a moving direction of the hand rail in the enclosure along the hand rail is provided.