Methods and related systems provide an interactive user interface in which CAD results are displayed in such a way that they may be used for both interpretation of detected abnormalities and for avoiding perceptual oversights. The output of a (multi-view) computer aided detection system is presented to the reader of a screening case in two phases: (1) an interactive phase, and (2) a prompting phase. In the first phase the reader can probe image locations for CAD information. In the second phase regions identified as relevant by the CAD system and not yet probed by the reader are prompted or displayed to the user, as these may have been overlooked by the reader. The CAD results can be calibrated to a probability of malignancy.
