Benedict, Suzanne,Manning, Mark,Murphy, Brian,Real, Sharon,Theuer, Charles
申请号:
NZ70510913
公开号:
NZ705109A
申请日:
2013.09.05
申请国别(地区):
NZ
年份:
2018
代理人:
摘要:
The present application relates to stable formulations comprising high concentrations of anti-CD 105 antibodies, antigen-binding fragments thereof, and a buffering agent, a polyol and having a pH of from about 4.0 to about 5.5. Another aspect relates to the use of the formulations in the manufacture of medicaments to reduce one or more signs or symptoms of an angiogenesis-related disorder such as cancers and ophthalmologic diseases.