Eric Walter Frederick Wolfgang Alton,Uta Griesenbach,Kamila Malgorzata Pytel,Michael Christian Paul-Smith,Ian Andrew Pringle,Stephen Charles Hyde,Deborah Rebecca Gill,Lee Adrian Davies,Alan Christophe
申请号:
US15312026
公开号:
US20170096684A1
申请日:
2015.04.23
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This invention relates to lentiviral gene transfer vectors pseudotyped with hemagglutinin-neuraminidase (HN) and fusion (F) proteins from a respiratory paramyxovirus, comprising a promoter and a transgene; and methods of making the same. The present invention also relates to the use of said vectors in gene therapy, particularly for the treatment of respiratory tract diseases such as Cystic Fibrosis (CF).