The present disclosure relates to compounds of formula I that are useful as modulators of a7 nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in Alzheimer’s disease, Parkinson’s disease, and schizophrenia, as well as for L-DOPA induced-dyskinesia and inflammation(I).本發明係關於可用作α7 nAChR調節劑之式I化合物、包含該等化合物之組合物,及該等化合物之用途,其用於預防、治療或改善疾病,特別是中樞神經系統病症(例如阿茲海默氏病(Alzheimer’s disease)、帕金森氏病(Parkinson’s disease)及精神分裂症中之認知損害),以及用於L-DOPA誘導之運動困難及發炎(I)。無
