Pharmaceutical compositions comprising at least one compound of e.g. the formulas(Ie) and a pharmaceutically acceptable carrier which is useful in a medicinewherein the symbols and substituents have the following meaning -X- is e.g. andY is e.g. or the pharmaceutically acceptable salts, esters or amides and prodrugsof the above identified compounds can be applied to modulate the in- vitro andin- vivo binding processes mediated by E-, P- or L-selectin binding.