There is a need for a selective, low-risk herbicide that can be used to control weeds in cereal cultures and turf. The present invention discloses that a bacterial secondary metabolite, thaxtomin and optionally another herbicide is an effective herbicide on broadleaved, sedge and grass weeds. Thaxtomin A and structurally similar compounds can be used as natural herbicides to control the germination and growth of weeds in cereal, turf grass, Timothy grass and pasture grass cultures with no phytotoxicity to these crops. As a natural, non-toxic compound, thaxtomin can be used as a safe alternative for weed control in both conventional and organic farming and gardening systems.需要一種可用於控制穀類培養物與草皮中雜草之低風險選擇性除草劑。本發明揭露一細菌次級代謝物薩克多敏(Thaxtomin)以及另一隨選除草成分,可做為闊葉雜草、莎草及禾草等雜草之有效除草劑。薩克多敏A與結構類似之化合物可做為天然除草劑,用以控制雜草於穀類、草皮草、貓尾草及牧草作物中之萌芽與生長,且不會對於作物產生毒害性。薩克多敏係天然無毒化合物,可於傳統及有機農作和園藝系統中做為替代性之安全雜草控制藥劑。