DIANTICORPS MONOVALENTS BISPÉCIFIQUES CAPABLES DE SE LIER À B7-H3 ET À CD3 ET LEURS UTILISATIONS

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专利权人:

Inc.;MacroGenics

发明人:

申请号：

EP16837560.8

公开号：

EP3337507A4

申请日:

2016.08.12

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

The present invention is directed to B7-H3×CD3 bispecific monovalent diabodies, and particularly, to B7-H3×CD3 bispecific monovalent Fc diabodies, that are capable of simultaneous binding to B7-H3 and CD3. The invention is also directed to pharmaceutical compositions that contain such bispecific monovalent Fc diabodies. The invention is additionally directed to methods for the use of such diabodies in the treatment of cancer and other diseases and conditions.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/