A new and distinct cultivar of blueberry plant named BB06-507MI-15 as described and shown herein. BB065-507MI-15 is a new and distinct high chill tetraploid Northern highbush blueberry (Vaccinium) variety of complex ancestry, based largely on V. corymbosum with a limited number of genes from V. darrowii, V. angustifolium, V. tenellum, and V. ashei. It is a productive early ripening variety that ripens approximately at the same time as Duke, and 10 days before Bluecrop. BB065-507MI-15 provides a very good yield potential, a very good plant vigor, fruit quality and firmness, as well as characteristics suitable to mechanical harvesting, and very good flavor and texture.