This invention relates to combinations comprising 3-[(R)-2-(N,N-dimethylamino)ethylthio-Sar]- 4-(gammahydroxymethylleucine)cyclosporine, or a pharmaceutically acceptable salt, solvate or hydrate thereof and certain nucleoside analogues, and their use in the treatment of hepatitis C virus.Esta invención se refiere a combinaciones que comprenden 3-[(3)-2-(N,N-Dimetilamino o una sal, solvato o hidrato farmacéuticamente aceptable de la misma y ciertos análogos de nucleosido, y su uso en el tratamiento de virus de hepatitis C.