3-HYDROXY-QUINAZOLINE-2,4-DIONE DERIVATIVES AND THEIR USE AS NUCLEASE MODULATORS

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专利权人:

Ludwig Institute for Cancer Research Ltd

发明人:

Timothy Gahman,Andrew Shiau,Richard Kolodner

申请号：

US15762527

公开号：

US20200237763A1

申请日:

2016.09.26

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Described inter alia are compounds according to formula (I): or a pharmaceutically acceptable salt thereof, and uses in methods for the modulation of flap endonuclease 1 (FEN1), Xeroderma Pigmentosum Complementation Group G protein (XPG), Exonuclease 1 (EXO1) and/or GEN1.

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