Timothy Grinstead;Gopi M. Venkatesh;James M. Clevenger
发明人:
Gopi M. Venkatesh,James M. Clevenger,Timothy Grinstead
申请号:
US12487339
公开号:
US08137734B2
申请日:
2009.06.18
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to a method of preparing an extended release pharmaceutical composition comprising cyclobenzaprine, comprising coating inert particles with a cyclobenzaprine-containing a drug layering composition to form IR beads, then coating the IR beads with an extended-release coating to form ER beads.