ALAN HERMAN,BRIAN MURPHY,DOUGLAS FARRAR,MARK MANNING
申请号：
BR112015000203
公开号：
BR112015000203A2
申请日:
2013.07.09
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
abstract the invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, with substantial reduction in sub-visible particles, and methods of manufacture of these compositions, methods of administration, and articles of manufacture. abstract of the patent abstract: "etanercept formulations exhibiting marked reduction in sub-visible particles". The invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long term storage of etanercept, with substantial reduction in sub-visible particles, and methods of manufacturing such compositions, methods of administration and articles of manufacture.abstract the invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, with substantial reduction in sub-visible particles, and methods of manufacture of these compositions, methods of administration, and articles of manufacture. tradução do resumo resumo patente de invenção: "formulações de etanercept que exibem redução marcada em partículas sub-visíveis". a invenção fornece composições de etanercept farmacêuticas aquosas estabilizadas adequadas para armazenamento de longo prazo de etanercept, com redução substancial em partículas sub-visíveis, e métodos de fabricação dessas composições, métodos de administração e artigos de fabricação.
