Yong Il Kim,Jung Hyun Cho,Jun Young Choi,Young Keun Choi,Jae Hyun Park,Jong Soo Woo
申请号:
US14421467
公开号:
US20150209290A1
申请日:
2013.08.30
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed are a bilayered composite tablet formation comprising (a) a first layer comprising irbesartan or a pharmaceutically acceptable salt thereof and (b) a second layer comprising atorvastatin or a pharmaceutically acceptable salt thereof and magnesium carbonate (MgCO3) in a weight ratio of 1:4 to 1:5, and a method for preparing the same. Exhibiting excellent dissolution rates and bioavailability, the bilayered composite tablet formulation is useful as a therapeutic for hypertension and hypercholesterolemia.