Compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of hyperproliferative, pain and inflammatory diseases. Methods of using compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.本發明提供適用於治療過度增生性、疼痛及發炎性疾病之式I化合物或其立體異構物、互變異構物、前藥或醫藥學上可接受之鹽。本發明揭露使用式I化合物或其立體異構物、互變異構物、前藥或醫藥學上可接受之鹽來活體外、原位及活體內診斷、預防或治療哺乳動物細胞之此等病症或相關病理學病狀的方法。
