INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY

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专利权人:

发明人:

RAEPPEL STÉPHANE,RAEPPEL FRANCK,CLARIDGE STEPHEN WILLIAM,ZHAN LIJIE,GAUDETTE FRÉDÉRIC,MANNION MICHAEL,SATO NORIFUMI,YUKI YOHEI,KISHIDA MASASHI,VAISBURG ARKADII

申请号：

IN3449/KOLNP/2012

公开号：

IN2012KN03449A

申请日:

2012.11.08

申请国别(地区):

IN

年份:

2013

代理人:

摘要：

Compounds that inhibit protein tyrosine kinase activity are disclosed, preferably of Formulae (II) and (III). In particular, said compounds inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling. The invention also provides said compounds, compositions thereof and methods for treating cell proliferative diseases and conditions and ophthalmic diseases, disorders and conditions.

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