The present invention relates to a pharmaceutical composition, characterized in that it comprises, as active ingredient, a combination of d-limonene, lupeol and a pharmaceutically active agent selected from cinnamaldehyde, epicatechin, methylhydroxychalcone polymer, beta-sitosterol, curcumin and mixtures thereof. It is suitable for use in the preventive and curative treatment of obesity, diabetes, dyslipidaemias, infections caused by infectious agents and the consequences thereof, and in invasive cancers, in particular those associated with adipose tissues.