<;P>;PROBLEM TO BE SOLVED: To provide a new compound useful as an agent such as a cell cycle inhibitor and an antibacterial agent, a cell-cycle progress inhibitor, a cell proliferation inhibitor, an antibacterial agent, an imipenem activity promoter, a bacterial cell proliferation inhibitor and a pharmaceutical composition containing the compound as an active component, a cell-cycle progress inhibition method, a cell proliferation inhibition method, an antibacterial method, an imipenem activity promotion method and a bacterial cell proliferation inhibition method using the compound, and an activity promoting agent and an activity promoting method for the compound. <;P>;SOLUTION: The naphthoquinone derivative compound or its pharmacologically permissible salt has a cell-cycle progress inhibiting activity, an antibacterial activity, an activity to promote imipenem action and a bacterial cell proliferation inhibiting activity. Imipenem has an action to promote the activity of naphthoquinone derivative compounds and their pharmacologically permissible salts. <;P>;COPYRIGHT: (C)2008,JPO&INPIT