In certain embodiments, a vial adaptor comprises a housing member, a connector configured to couple the adaptor with a vial, and an extractor channel formed in the housing member. The extractor channel is configured to facilitate withdrawal of fluid from the vial when the adaptor is coupled to the vial. In some embodiments, an anti-reflux valve is positioned within the extractor channel. The anti-reflux valve can be configured to impede or obstruct fluid returning to a fluid source after withdrawal of the fluid from the fluid source.在某些實施例中,一種藥水瓶配接器包含一外殼構件;一連接器,其經組態以耦接該配接器與一藥水瓶;及一抽取器通道,其形成於該外殼構件中。該抽取器通道經組態以在將該配接器耦接至該藥水瓶時促進自該藥水瓶抽出流體。在一些實施例中,一防逆流閥定位於該抽取器通道內。該防逆流閥可經組態以在自一流體源抽出該流體之後阻止或阻塞流體返回至該流體源。100...系統110...藥水瓶112...本體114...蓋116...醫療流體118...無菌空氣120...抽取器122...導管130...調節器132...袋134...導管140...交換設備142...注射器144...注射器柱塞150...儲集器