Jeffrey T. L. Smith;Ethan W. Ojala;John A. Latham;Benjamin H. Dutzar;Leon F. Garcia-Martinez
发明人:
Leon F. Garcia-Martinez,Benjamin H. Dutzar,Ethan W. Ojala,Jeffrey T. L. Smith,John A. Latham
申请号:
US13308831
公开号:
US09783601B2
申请日:
2011.12.01
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Monovalent agents, including Fab fragments and monovalent monoclonal antibodies analogous to MetMab, having binding specificity to human Nerve Growth Factor (“NGF”), and methods treating pain in an individual wherein there is no substantial increase in the inflammatory response of the individual following administration of the monovalent agents.