[Problem to be solved] The present invention is to provide a gastrointestinal composition, of which the therapeutic effect is remarkably enhanced.[Solution] This composition comprising Vitamin U and Atractylodes lancea De Candolle or Atractylodes chinensis Koidzumi is particularly used for inhibiting a feeling of belch, nausea, vomiting and for reducing a feeling of breast obstruction, stomach oppression, indigestion, gastric distension or inappetence.本發明係提供,作為胃腸藥之效果係顯著增強之胃腸藥。本發明係提供一種胃腸藥組成物,其含有維生素U(Methylmethionine Sulfonium Chloride;MMSC)以及蒼朮之胃腸藥組成物,特別是為了緩解飽嗝、想吐、噁心或甚至嘔吐之抑制,或胸壓迫感、胃脹、消化不良、胃部.腹部膨脹感或食欲不振種種者。