The present invention comprises both meloxicam and xylazine containing compositions and methods of their administration in the field of veterinary pharmaceuticals. A meloxicam and xylazine formulation is provided which is adapted for oral administration. A method is also provided to form a combination meloxicam and xylazine formulation from meloxicam and xyalzine formulations including directions as to concentrations and dosages for sheep and cattle, the target species for the formulations.