5 - amino [1,4], tiazines as BACE1 inhibitors； use of compound against Alzheimer's disease.

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专利权人:

F.HOFFMANN-LA ROCHE AG

发明人:

HILPERT HANS,WOLTERING THOMAS

申请号：

CL2014003123

公开号：

CL2014003123A1

申请日:

2014.11.18

申请国别(地区):

CL

年份:

2015

代理人:

摘要：

The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.COMPUESTOS DERIVADOS DE N-(3-(5-AMINO-3,6-DIHIDRO-2H-1,4-TIAZIN-3-IL)FENIL)AMIDA COMO INHIBIDORES DE BACE 1； COMPOSICIÓN FARMACÉUTICA； Y USO DEL COMPUESTO CONTRA LA ENFERMEDAD DE ALZHEIMER.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/