A drug delivery device (1 100 200) comprising a housing (2 102 201, 202), a dose setting mechanism operable to set a dose to be delivered from a variable volume reservoir, and a dose delivery structure (60 160 260) activatable to expel a set dose. The dose setting mechanism comprises a dose indicating structure (40 140 240) for indicating a size of the set dose. The dose indicating structure (40 140 240) is coupled with the dose delivery structure (60 160 260) during expelling of the set dose and moved relative to the housing (2 102 201, 202) to a zero dose indicating position. The zero dose indicating position is a position which is fixed with respect to the housing (2 102 201, 202). The dose setting mechanism further comprises a dose setting structure (20 120 220) movable in a dose preparing direction relative to the housing (2 102 201, 202) to a dose prepared position to set a dose of a first size. The dose prepared position is a position along the dose preparing direction which is fixed with respect to the housing (2 102 201, 202). The dose setting structure (20 120 220) and the dose indicating structure (40 140 240) are coupled and configured to undergo first correlated displacements relative to the housing (2 102 201, 202) during movement of the dose indicating structure (40 140 240) to the zero dose indicating position and further coupled and configured to undergo second correlated displacements relative to the housing (2 102 201, 202) during movement of the dose setting structure (20 20 220) to the dose prepared position, where the first correlated displacements and the second correlated displacements are mutually reverse. Further, when the dose setting structure (20 120 220) is in the dose prepared position the dose indicating structure (40 140 240) is selectively displaceable relative to the housing (2 102 201, 202) while the dose setting structure (20 120 220) remains stationary in the dose preparing direction to allow adjustment of the dose of the first
