PROBLEM TO BE SOLVED: To provide a new therapeutic agent for a panreas cancer.SOLUTION: Provided is a combined medicine consisting of an therapeutically effective amount of a compound (1) represented by the following formula (1) or phamaceutically acceptable salt thereof, and gemcitabine. Use of the treatment includes an administration of the compound (1) in a therapeutically effective amount of 400 ng-hr/ml to 9,000 ng-hr/ml.【課題】膵臓癌の新規な治療剤の提供。【解決手段】治療的有効量の下記式(1):を有する化合物(1)又は医薬的に許容できるその塩、及びゲムシタビンを含んで成る組合せ医薬。400ng-時/ml~9000ng-時/mlの治療的有効量の化合物(1)を投与することを含んで成る。【選択図】なし