Disclosed are a sympatholytic agent which can suppress the activity of a sympathetic nerve more effectively, a cosmetic, a food and a sundry. Ethyl 4-methoxybenzoate can calm down the activity of a sympathetic nerve. The sympatholytic agent, the cosmetic, the food and the sundry can suppress the activity of a sympathetic nerve effectively.本發明之課題在於提供一種可更有效地抑制交感神經之活動的交感神經抑制劑、化妝料、食品及雜貨。4-甲氧基苯甲酸乙酯使交感神經之活動鎮靜化。因此,本發明之交感神經抑制劑、化妝料、食品及雜貨可有效地抑制交感神經之活動。