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DOSING REGIMENS FOR ANTI-TF-ANTIBODY DRUG-CONJUGATES
专利权人:
Genmab A/S
发明人:
LISBY, Steen,WHITING, Nancy Cherry
申请号:
EP16765958
公开号:
EP3347054A1
申请日:
2016.09.09
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Anti-TF antibody drug conjugate and pharmaceutical compositions comprising the antibody drug-conjugate for use in the treatment of a solid cancer comprising administering to a subject a weekly dose of from about 0.8 mg/kg to about 1.8 mg/kg of an anti-TF antibody drug conjugate once a week for three consecutive weeks followed by a one week resting period without any administration of anti-TF ADC so that each cycle time is 28 days including the resting period.
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