The present disclosure relates to a bispecific antibody comprising at least one antigen binding site specific for DR5 and at least one antigen binding site specific for FAP, an antibody specific for DR5, and methods for producing these , Pharmaceutical compositions containing the antibodies, and uses thereof. [Selection figure] None本開示は、DR5に特異的な少なくとも1個の抗原結合部位と、FAPに特異的な少なくとも1個の抗原結合部位とを含む二重特異性抗体、DR5に特異的な抗体、これらの産生方法、前記抗体を含有する薬学的組成物、及びこれらの使用に関する。【選択図】なし